Fig. 1 · Structure

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MS-PEG4-THP

PROTAC Linker

MS-PEG4-THP is a polyethylene glycol (PEG)-based linker specifically designed for the synthesis of PROTAC (proteolysis-targeting chimera) compounds. This linker enhances the design and efficacy of PROTACs by facilitating the targeted degradation of specific proteins within the cell. Its structural properties support research applications in cellular signaling, protein homeostasis, and the development of novel therapeutic strategies for various diseases.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 145927-73-7
Applications PROTAC Linker
Formula C14H28O8S
Molecular Weight 356.43
SMILES
CS(=O)(OCCOCCOCCOCCOC1CCCCO1)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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