MS023

Catalog No.: A12585

PRMT1 inhibitor

MS023 Chemical Structure

CAS NO. 1831110-54-3

MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.

Availability: In stock

Package Price Qty
5 mg
$90.00
10 mg
$150.00
25 mg
$300.00
Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.

Biological Activity

MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.
Targets
PRMT6 PRMT8 PRMT1 PRMT4 PRMT3
4 nM5 nM30 nM83 nM119 nM
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.79 mL 173.97 mL 347.95 mL
0.5 mM 6.96 mL 34.79 mL 69.59 mL
1 mM 3.48 mL 17.4 mL 34.79 mL
5 mM 0.7 mL 3.48 mL 6.96 mL

*The above data is based on the productmolecular weight 287.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12585
Actions Inhibitor
M. Wt 287.4
Formula C17H25N3O
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 1831110-54-3
Synonyms MS-023, MS 023
SMILES NCCN(C)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2

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