MS023

Catalog No.: A12585

PRMT1 inhibitor

MS023

MS023 Chemical Structure

CAS NO. 1831110-54-3

MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.

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Package Price Qty
5 mg
$90.00
10 mg
$150.00
25 mg
$300.00
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Biological Activity

MS023 is a potent inihbitor of PRMTs 1,3,4,6,and 8 (IC50 = 30, 119, 83, 8, and 8 nM, respectively), which are responsible for asymmetric dimethylation of arginine residues.
Targets
PRMT6 PRMT8 PRMT1 PRMT4 PRMT3
4 nM5 nM30 nM83 nM119 nM
In vitro DMSO 50 mg/mL (173.96 mM)
Water Insoluble
Ethanol 50 mg/mL (173.96 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 34.79 mL 173.97 mL 347.95 mL
0.5 mM 6.96 mL 34.79 mL 69.59 mL
1 mM 3.48 mL 17.4 mL 34.79 mL
5 mM 0.7 mL 3.48 mL 6.96 mL

*The above data is based on the productmolecular weight 287.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12585
Actions Inhibitor
CAS No. 1831110-54-3
Formula C17H25N3O
M. Wt 287.4
Solubility DMSO
Purity >98%
Synonyms MS-023, MS 023
SMILES NCCN(C)CC1=CNC=C1C2=CC=C(OC(C)C)C=C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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