MS023 trihydrochloride is a potent and selective inhibitor of human type I protein arginine methyltransferases (PRMTs), demonstrating impressive IC50 values of 30 nM for PRMT1, 119 nM for PRMT3, 83 nM for PRMT4, 4 nM for PRMT6, and 5 nM for PRMT8. Its ability to effectively inhibit these enzymes makes it a valuable tool for research into the roles of PRMTs in various biological processes and disease states. This compound is suitable for studies involving cellular signaling, epigenetics, and post-translational modifications.
MS023 trihydrochloride is a potent and selective inhibitor of human type I protein arginine methyltransferases (PRMTs), demonstrating impressive IC50 values of 30 nM for PRMT1, 119 nM for PRMT3, 83 nM for PRMT4, 4 nM for PRMT6, and 5 nM for PRMT8. Its ability to effectively inhibit these enzymes makes it a valuable tool for research into the roles of PRMTs in various biological processes and disease states. This compound is suitable for studies involving cellular signaling, epigenetics, and post-translational modifications.
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