MSK-195 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) channel, demonstrating a potency of 120 nM and an efficacy of 71% in inducing arteriolar responses. This compound is valuable for research applications aimed at understanding pain pathways, neurogenic inflammation, and the physiological role of TRPV1 in various tissues. Its ability to selectively activate TRPV1 makes it a useful tool for dissecting the functions and mechanisms associated with this receptor in preclinical studies.
MSK-195 is a potent agonist of the transient receptor potential vanilloid 1 (TRPV1) channel, demonstrating a potency of 120 nM and an efficacy of 71% in inducing arteriolar responses. This compound is valuable for research applications aimed at understanding pain pathways, neurogenic inflammation, and the physiological role of TRPV1 in various tissues. Its ability to selectively activate TRPV1 makes it a useful tool for dissecting the functions and mechanisms associated with this receptor in preclinical studies.
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