mTOR inhibitor-10 (Compound 9c) is a selective inhibitor targeting the mechanistic target of rapamycin (mTOR). This compound effectively inhibits both mTOR and PI3K-α, demonstrating IC50 values of 0.7 nM and 825 nM, respectively. mTOR inhibitor-10 exhibits significant anti-proliferative activity against LNCaP cancer cells, with an IC50 value of 87 nM, making it a valuable tool for research in cancer biology and therapeutic applications.
mTOR inhibitor-10 (Compound 9c) is a selective inhibitor targeting the mechanistic target of rapamycin (mTOR). This compound effectively inhibits both mTOR and PI3K-α, demonstrating IC50 values of 0.7 nM and 825 nM, respectively. mTOR inhibitor-10 exhibits significant anti-proliferative activity against LNCaP cancer cells, with an IC50 value of 87 nM, making it a valuable tool for research in cancer biology and therapeutic applications.
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