mTOR inhibitor-16 (Compound 9f) is a selective inhibitor of the mechanistic target of rapamycin (mTOR). It demonstrates potent inhibitory activity against mTOR and PI3K-α, with IC50 values of 1.25 nM and 82 nM, respectively. This compound effectively inhibits the proliferation of LNCaP prostate cancer cells, with an IC50 of 140 nM, making it a valuable tool for cancer research and studies involving the mTOR signaling pathway.
mTOR inhibitor-16 (Compound 9f) is a selective inhibitor of the mechanistic target of rapamycin (mTOR). It demonstrates potent inhibitory activity against mTOR and PI3K-α, with IC50 values of 1.25 nM and 82 nM, respectively. This compound effectively inhibits the proliferation of LNCaP prostate cancer cells, with an IC50 of 140 nM, making it a valuable tool for cancer research and studies involving the mTOR signaling pathway.
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