mTORC1-IN-2

Catalog No.: A79761
mTORC1 Inhibitor
mTORC1-IN-2 is an inhibitor of the mechanistic target of rapamycin complex 1 (mTORC1). This compound functions by upregulating the expression of TSC2-P while concurrently inhibiting mTORC1 signaling. It exhibits vasodilatory effects and offers protection against myocardial hypoxic injury, making it a valuable tool for research in cardiovascular and metabolic disorders. Its impact on mTORC1 signaling pathways underscores its potential in studies related to cellular growth, proliferation, and survival.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionmTORC1-IN-2 is an inhibitor of the mechanistic target of rapamycin complex 1 (mTORC1). This compound functions by upregulating the expression of TSC2-P while concurrently inhibiting mTORC1 signaling. It exhibits vasodilatory effects and offers protection against myocardial hypoxic injury, making it a valuable tool for research in cardiovascular and metabolic disorders. Its impact on mTORC1 signaling pathways underscores its potential in studies related to cellular growth, proliferation, and survival.
Product Information
Catalog NumA79761
FormulaC16H15N3O6
Molecular Weight345.31
CAS Number2974368-96-0
SMILESO=NN(C)C1=CC=C(C=C1)OC(OCC2=C(C)C=C([N+]([O-])=O)C=C2)=O
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