Mudanpioside E is a paeoniflorin-type monoterpene glycoside that acts as an antiallergic agent by inhibiting IgE-mediated β-hexosaminidase release with an IC50 of 40.34 μM. It effectively reverses the inhibitory effect of modified extracts of the Xiaoqinglong Decoction on passive cutaneous anaphylaxis in murine models. While Mudanpioside E does not exhibit direct activity against passive cutaneous anaphylaxis, it serves as a valuable tool for research investigating allergic diseases and potential therapeutic strategies.
Mudanpioside E is a paeoniflorin-type monoterpene glycoside that acts as an antiallergic agent by inhibiting IgE-mediated β-hexosaminidase release with an IC50 of 40.34 μM. It effectively reverses the inhibitory effect of modified extracts of the Xiaoqinglong Decoction on passive cutaneous anaphylaxis in murine models. While Mudanpioside E does not exhibit direct activity against passive cutaneous anaphylaxis, it serves as a valuable tool for research investigating allergic diseases and potential therapeutic strategies.
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