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Mulberrofuran D

PTP1B Inhibitor

Mulberrofuran D is a potent inhibitor of protein tyrosine phosphatase 1B (PTP1B), exhibiting an IC50 value of 11.61 μM and a Ki of 4.79 μM against human PTP1B. This compound is primarily utilized in research focused on type 2 diabetes, serving as a valuable tool for investigating insulin signaling pathways and potential therapeutic interventions. Its selective inhibition of PTP1B positions Mulberrofuran D as a significant reagent for studying metabolic disorders.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	83474-71-9
Applications	PTP1B Inhibitor
Formula	C₂₉H₃₄O₄
Molecular Weight	446.58
SMILES	C/C(C)=C\CC/C(C)=C/CC1=C2C(C=C(C3=C(C(O)=CC(O)=C3)C/C=C(C)\C)O2)=CC=C1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.