Muurol-4-ene-3,8-dione is a sesquiterpene that acts as a hepatotoxic agent, primarily derived from Eupatorium adenophorum. It exhibits inhibitory effects on the growth of normal human hepatocytes (L02) and human hepatocellular carcinoma cells (HepG2), demonstrating IC50 values of 87.52 μM and 104.48 μM, respectively. This compound is valuable for research on liver toxicity and cancer biology, providing insights into hepatocyte responses and potential therapeutic targets.
Muurol-4-ene-3,8-dione is a sesquiterpene that acts as a hepatotoxic agent, primarily derived from Eupatorium adenophorum. It exhibits inhibitory effects on the growth of normal human hepatocytes (L02) and human hepatocellular carcinoma cells (HepG2), demonstrating IC50 values of 87.52 μM and 104.48 μM, respectively. This compound is valuable for research on liver toxicity and cancer biology, providing insights into hepatocyte responses and potential therapeutic targets.
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