MY-1076 is a selective inhibitor of the Yes-associated protein (YAP), which plays a critical role in various cellular processes, including cell proliferation and apoptosis. This compound promotes the degradation of YAP, leading to induced apoptosis in tumor cells. MY-1076 demonstrates potent antiproliferative effects against gastric and colorectal cancer cell lines, including MGC-803, SGC-7901, HCT-116, and KYSE450, with IC50 values of 0.019, 0.017, 0.020, and 0.044 μM, respectively. It is a valuable tool for researching YAP's role in cancer biology and potential therapeutic interventions.
MY-1076 is a selective inhibitor of the Yes-associated protein (YAP), which plays a critical role in various cellular processes, including cell proliferation and apoptosis. This compound promotes the degradation of YAP, leading to induced apoptosis in tumor cells. MY-1076 demonstrates potent antiproliferative effects against gastric and colorectal cancer cell lines, including MGC-803, SGC-7901, HCT-116, and KYSE450, with IC50 values of 0.019, 0.017, 0.020, and 0.044 μM, respectively. It is a valuable tool for researching YAP's role in cancer biology and potential therapeutic interventions.
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