Fig. 1 · Structure
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Myxochelin A
Cat. No.
A76490
CAS
120243-02-9
Lipoxygenase Inhibitor
Myxochelin A is a potent lipoxygenase inhibitor derived from the microbial metabolite of A. disciformis. It demonstrates significant antibacterial activity against Gram-positive bacteria, including B. cereus, S. aureus, and M. luteus, while exhibiting no activity against Gram-negative bacteria or fungi in agar diffusion assays. Additionally, Myxochelin A inhibits 5-lipoxygenase (5-LO) with an IC50 of 1.9 μM for recombinant human enzymes and shows cytotoxic effects on 26-L5 colon cancer cells at a concentration of 3 μg/mL, making it a valuable compound for research in inflammation and cancer biology.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 120243-02-9 |
| Applications | Lipoxygenase Inhibitor |
| Formula | C20H24N2O7 |
| Molecular Weight | 404.41 |
| Synonyms | (S)-Myxochelin A |
| SMILES | OC[C@@H](NC(C1=CC=CC(O)=C1O)=O)CCCCNC(C2=CC=CC(O)=C2O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
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| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.