N-1518

Catalog No.: A58604
Adrenergic Receptor Blocker
N-1518 is an adrenergic receptor blocker that exhibits competitive antagonism at both α1 and β1 receptors, with approximately 20-fold selectivity for α1. This compound demonstrates vasodilatory effects, making it a valuable tool for investigating hypertension treatment and related cardiovascular research applications. N-1518 offers insights into the differential roles of adrenergic receptors in physiological processes and therapeutic interventions.
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5mg
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-1518 is an adrenergic receptor blocker that exhibits competitive antagonism at both α1 and β1 receptors, with approximately 20-fold selectivity for α1. This compound demonstrates vasodilatory effects, making it a valuable tool for investigating hypertension treatment and related cardiovascular research applications. N-1518 offers insights into the differential roles of adrenergic receptors in physiological processes and therapeutic interventions.
Product Information
Catalog NumA58604
FormulaC22H26N2O5
Molecular Weight398.45
CAS Number93750-14-2
SMILESO=C1NC=C(C2=C1C=CC=C2)OCC(CNC(COC3=C(OC)C=CC=C3)C)O
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