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N-(3-Hydroxypropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide

PROTAC Linker

N-(3-Hydroxypropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide serves as a versatile PROTAC linker, facilitating the development of proteolysis-targeting chimeras (PROTACs). Its structure enables efficient conjugation to target ligands, enhancing target protein degradation pathways. This linker is essential for researchers engaged in drug discovery and therapeutic interventions focused on targeted protein regulation.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1449134-30-8
Applications	PROTAC Linker
Formula	C₁₆H₂₄BNO₄
Molecular Weight	305.18
SMILES	O=C(NCCCO)C1=CC=C(C=C1)B2OC(C)(C)C(O2)(C)C

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.