N-Acetyl-D-mannosamine

Catalog No.: A18584

N-Acetyl-D-mannosamine

N-Acetyl-D-mannosamine Chemical Structure

CAS NO. 3615-17-6

N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA). N-Acetyl-D-mannosamine (ManNAc) can be metabolized by GNE and GlcNAc 2-epimerase (Renin binding protein, RnBP), into ManNAc-6-phosphate and GlcNAc, respectively.? N-Acetyl-d-mannosamine (ManNAc) and its derivatives activates hypocretin (HCRT) gene expression in the orexin neurons, providing a potential model for the testing of a therapy for neural disorders.

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Biological Activity

N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA). N-Acetyl-D-mannosamine (ManNAc) can be metabolized by GNE and GlcNAc 2-epimerase (Renin binding protein, RnBP), into ManNAc-6-phosphate and GlcNAc, respectively.? N-Acetyl-d-mannosamine (ManNAc) and its derivatives activates hypocretin (HCRT) gene expression in the orexin neurons, providing a potential model for the testing of a therapy for neural disorders.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 45.21 mL 226.03 mL 452.06 mL
0.5 mM 9.04 mL 45.21 mL 90.41 mL
1 mM 4.52 mL 22.6 mL 45.21 mL
5 mM 0.9 mL 4.52 mL 9.04 mL

*The above data is based on the productmolecular weight 221.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18584
M. Wt 221.21
Formula C8H15NO6
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 3615-17-6
SMILES OC[[email protected]@H](O)[[email protected]@H](O)[[email protected]](O)[[email protected]@H](C=O)NC(C)=O

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