N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a versatile tool for modular assembly in chemical biology research.
N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based linker designed for use in the synthesis of PROTACs. This compound features an azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a versatile tool for modular assembly in chemical biology research.
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