Fig. 1 · Structure

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N-(Amino-PEG3)-N-bis(PEG3-acid)

PROTAC Linker

N-(Amino-PEG3)-N-bis(PEG3-acid) is a PEG-based linker designed for use in the synthesis of PROTACs (proteolysis-targeting chimeras). This compound facilitates the assembly of complex biomolecular constructs by providing a flexible and water-soluble connection, enhancing cellular permeability and targeting specificity. It is ideal for applications in drug discovery and development focused on targeted protein degradation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2055042-59-4
Applications PROTAC Linker
Formula C26H52N2O13
Molecular Weight 600.70
SMILES
O=C(O)CCOCCOCCOCCN(CCOCCOCCOCCN)CCOCCOCCOCCC(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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