Fig. 1 · Structure

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N-(Amino-PEG4)-N-Biotin-PEG4-acid

PROTAC Linker

N-(Amino-PEG4)-N-Biotin-PEG4-acid functions as a biotin-labeled, polyethylene glycol (PEG) linker for protein degradation targeting chimera (PROTAC) synthesis. This compound facilitates the conjugation of biotin to target proteins, enhancing their degradation through the ubiquitin-proteasome pathway. It is suitable for research applications involving targeted protein degradation and characterization of biotinylated proteins.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2100306-84-9
Applications PROTAC Linker
Formula C31H58N4O12S
Molecular Weight 710.88
SMILES
O=C(O)CCOCCOCCOCCOCCN(CCOCCOCCOCCOCCN)C(CCCC[C@H]1SC[C@@]([C@@]1([H])N2)([H])NC2=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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