N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester functions as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs. This compound serves as a click chemistry reagent, featuring an azide group that can engage in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, interacting with DBCO or BCN functionalized molecules. Its versatile reactive groups enable broad applications in chemical biology and drug development research.
N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester functions as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs. This compound serves as a click chemistry reagent, featuring an azide group that can engage in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions, interacting with DBCO or BCN functionalized molecules. Its versatile reactive groups enable broad applications in chemical biology and drug development research.
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