N-(Azido-PEG3)-N-Boc-PEG3-acid is a versatile PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide moiety, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a valuable tool for modular assembly in chemical biology research.
N-(Azido-PEG3)-N-Boc-PEG3-acid is a versatile PEG-based linker designed for the synthesis of PROTACs, facilitating targeted protein degradation. This compound features an azide moiety, allowing it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can engage in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN-functionalized compounds, making it a valuable tool for modular assembly in chemical biology research.
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