N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based linker designed for use in the synthesis of PROTAC molecules. Functioning as a click chemistry reagent, it features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, facilitating the development of targeted protein degradation strategies in chemical biology research.
N-(Azido-PEG4)-N-bis(PEG4-t-butyl ester) is a PEG-based linker designed for use in the synthesis of PROTAC molecules. Functioning as a click chemistry reagent, it features an azide group that enables copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne-containing compounds. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized molecules, facilitating the development of targeted protein degradation strategies in chemical biology research.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
