N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide moiety, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing substrates. Additionally, it is suitable for strain-promoted alkyne-azide cycloaddition (SPAAC) with trans-cyclooctene derivatives, allowing for versatile conjugation strategies in chemical biology studies.
N-(Azido-PEG4)-N-Boc-PEG4-Boc is a PEG-based PROTAC linker that facilitates the synthesis of proteolysis-targeting chimeras (PROTACs). This compound features an azide moiety, enabling it to participate in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing substrates. Additionally, it is suitable for strain-promoted alkyne-azide cycloaddition (SPAAC) with trans-cyclooctene derivatives, allowing for versatile conjugation strategies in chemical biology studies.
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