N-Boc-N-bis(PEG3-azide) is a PEG-based PROTAC linker that facilitates the synthesis of targeted protein degraders. This compound features an azide group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it a versatile tool for researchers in the field of protein degradation and chemical biology.
N-Boc-N-bis(PEG3-azide) is a PEG-based PROTAC linker that facilitates the synthesis of targeted protein degraders. This compound features an azide group, enabling it to engage in copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. Additionally, it can participate in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with DBCO or BCN functionalized compounds, making it a versatile tool for researchers in the field of protein degradation and chemical biology.
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