Fig. 1 · Structure

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N-Boc-N-bis-PEG5

PROTAC Linker

N-Boc-N-bis-PEG5 is a polyethylene glycol (PEG)-based linker designed for use in the synthesis of Proteolysis Targeting Chimeras (PROTACs). This compound facilitates the selective degradation of target proteins through the recruitment of E3 ligases, offering significant potential in therapeutic development. Its unique structure enhances solubility and biocompatibility, making it a valuable tool for research applications focused on targeted protein degradation and disease modulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2093154-02-8
Applications PROTAC Linker
Formula C25H51NO12
Molecular Weight 557.67
SMILES
O=C(OC(C)(C)C)N(CCOCCOCCOCCOCCO)CCOCCOCCOCCOCCO

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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