Fig. 1 · Structure
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N-Boc-PEG10-alcohol
PROTAC Linker
N-Boc-PEG10-alcohol is a polyethylene glycol (PEG)-based linker designed for the construction of PROTACs (proteolysis-targeting chimeras). This compound facilitates the selective degradation of target proteins by linking a ligand for the target protein to an E3 ubiquitin ligase. Its application in PROTAC synthesis underscores its significance in the development of targeted protein degradation strategies for therapeutic intervention.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2238844-74-9 |
| Applications | PROTAC Linker |
| Formula | C25H51NO12 |
| Molecular Weight | 557.67 |
| SMILES | O=C(OC(C)(C)C)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCO |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.