Fig. 1 · Structure
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N-Boc-undecane-1,11-diamine
PROTAC Linker
N-Boc-undecane-1,11-diamine is a PROTAC linker featuring a terminal amine and Boc-protected amino groups. This compound serves a pivotal role in the synthesis of PROTACs and facilitates various conjugation applications due to its reactive amine group, which can interact with carboxylic acids, activated NHS esters, and carbonyl compounds. The Boc group can be easily removed under mild acidic conditions to yield the free amine, enabling further functionalization and incorporation into complex biological systems. This reagent is essential for researchers focusing on targeted protein degradation and related bioconjugation strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 937367-26-5 |
| Applications | PROTAC Linker |
| Formula | C16H34N2O2 |
| Molecular Weight | 286.45 |
| SMILES | O=C(OC(C)(C)C)NCCCCCCCCCCCN |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.