N-Desmethyl rosiglitazone

Catalog No.: A40181
Drug Metabolite
N-Desmethyl rosiglitazone is a drug metabolite resulting from the demethylation of Rosiglitazone via the cytochrome P450 enzyme system in liver microsomes. This compound exhibits partial agonist activity at the peroxisome proliferator-activated receptor gamma (PPARγ), making it valuable for research into the metabolism and pharmacokinetics of Rosiglitazone. It serves as a useful tool for examining the pharmacological effects and metabolic pathways associated with thiazolidinedione drugs.
Grouped product items
Size Price Stock Qty
1mg
$240.00
In stock
5mg
$740.00
In stock
10mg
$1,210.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
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Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
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Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Desmethyl rosiglitazone is a drug metabolite resulting from the demethylation of Rosiglitazone via the cytochrome P450 enzyme system in liver microsomes. This compound exhibits partial agonist activity at the peroxisome proliferator-activated receptor gamma (PPARγ), making it valuable for research into the metabolism and pharmacokinetics of Rosiglitazone. It serves as a useful tool for examining the pharmacological effects and metabolic pathways associated with thiazolidinedione drugs.
Product Information
Catalog NumA40181
FormulaC17H17N3O3S
Molecular Weight343.40
CAS Number257892-31-2
SMILESO=C1SC(CC2=CC=C(C=C2)OCCNC3=NC=CC=C3)C(N1)=O
SynonymsSB 237216
Useful Calculator

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Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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