N-Desmethyl Zolmitriptan is an active metabolite that selectively targets the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D. It acts as an agonist of the 5-HT1B receptor, facilitating vasoconstriction in isolated human cerebral arteries, with an EC50 of approximately 100 nM. This compound is valuable for research into migraine mechanisms and the exploration of serotonin signaling pathways.
N-Desmethyl Zolmitriptan is an active metabolite that selectively targets the serotonin (5-HT) receptor subtypes 5-HT1B and 5-HT1D. It acts as an agonist of the 5-HT1B receptor, facilitating vasoconstriction in isolated human cerebral arteries, with an EC50 of approximately 100 nM. This compound is valuable for research into migraine mechanisms and the exploration of serotonin signaling pathways.
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