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N-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE

Catalog No.: A43004
ADC Linker
N-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE is an ADC linker designed for targeted cancer therapy. This compound facilitates the conjugation of cytotoxic agents to antibodies, enhancing selectivity and efficacy in tumor cells. Its utilization in antibody-drug conjugates provides a valuable tool for researchers investigating cancer treatments and mechanisms in various preclinical studies.
N-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE 2892440-83-2 ADC Linker
Grouped product items
Size Price Stock Qty
1mg
$1,160.00
In stock
5mg
$2,950.00
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Research use only. We do not sell to patients.
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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Di(D-mannose)-PEG12-MC-VC-PAB-MMAE is an ADC linker designed for targeted cancer therapy. This compound facilitates the conjugation of cytotoxic agents to antibodies, enhancing selectivity and efficacy in tumor cells. Its utilization in antibody-drug conjugates provides a valuable tool for researchers investigating cancer treatments and mechanisms in various preclinical studies.
Product Information
Catalog NumA43004
FormulaC113H194N14O39
Molecular Weight2372.82
CAS Number2892440-83-2
SMILESO[C@H]([C@H](NC([C@@H]([C@@H](OC)[C@]1(N(C(C[C@H]([C@@H](N(C([C@@H](NC([C@@H](N(C(OCC2=CC=C(NC([C@@H](NC([C@@H](NC([C@@H](NC(CCCCCN3C(C=CC3=O)=O)=O)CCCCNC(CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN(C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)C[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C2)=O)C)C(C)C)=O)C(C)C)=O)C)[C@H](CC)C)OC)=O)CCC1)[H])C)=O)C)C4=CC=CC=C4
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Antibody-drug Conjugates (ADC) > ADC Linker