Fig. 1 · Structure

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N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5

PROTAC Linker

N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a PEG-based PROTAC linker designed for efficient protein degradation applications. This compound facilitates the synthesis of PROTACs, enabling targeted degradation of specific proteins through the ubiquitin-proteasome system. Its fluorogenic properties allow for specific detection and tracking in cellular assays, making it an essential tool for researchers investigating targeted protein modulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2107273-30-1
Applications PROTAC Linker
Formula C49H68ClN3O12
Molecular Weight 926.53
SMILES
CC(C1=CC=CC=C1N/2CCOCCOCCOCCOC)(C)C2=C/C=C/C=C/C3=[N+](CCOCCOCCOCCOCCC(ON4C(CCC4=O)=O)=O)C(C=CC=C5)=C5C3(C)C.[Cl-]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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