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N-Mal-N-bis(PEG4-amine)

PROTAC Linker

N-Mal-N-bis(PEG4-amine) is a polyethylene glycol (PEG) based linker designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). This linker facilitates the recruitment of E3 ligases, enhancing target protein degradation via the ubiquitin-proteasome pathway. Its versatility makes it suitable for research applications focused on targeted protein degradation and therapeutic development in various disease models.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2128735-22-6
Applications	PROTAC Linker
Formula	C₂₇H₅₀N₄O₁₁
Molecular Weight	606.71
SMILES	O=C(N(CCOCCOCCOCCOCCN)CCOCCOCCOCCOCCN)CCN1C(C=CC1=O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.