Fig. 1 · Structure

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N,N-dimethyldithiocarbamate potassium

Cat. No. B21296 CAS 128-03-0

ubiquitin activating enzyme E1 Inhibitor

N,N-dimethyldithiocarbamate potassium is an inhibitor of the ubiquitin-activating enzyme E1, leading to a decrease in the levels of activated ubiquitinated E1 (ub-E1). This compound is known to elevate intracellular copper levels, enhance oxidative stress, raise protein carbonyl levels, and promote the expression of heme oxygenase-1 (HO-1). N,N-dimethyldithiocarbamate potassium is particularly relevant for research into neurodegenerative disorders, including Parkinson's disease, by elucidating the impact of ubiquitin pathways on cellular stress responses.

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Specifications

Manufacturer Adooq Bioscience
Actions Inhibitor
CAS Number 128-03-0
Applications ubiquitin activating enzyme E1 Inhibitor
Formula C3H6KNS2
Molecular Weight 159.31
SMILES
S=C(N(C)C)S[K]

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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