N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an alkyne moiety that enables efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application in PROTAC development facilitates targeted protein degradation, making it a valuable tool for researchers in drug discovery and chemical biology.
N-(Propargyl-PEG2)-N-Boc-PEG3-t-butyl ester is a PEG-based linker designed for use in the synthesis of PROTACs (Proteolysis Targeting Chimeras). This compound features an alkyne moiety that enables efficient click chemistry through copper-catalyzed azide-alkyne cycloaddition (CuAAc) with azide-containing molecules. Its application in PROTAC development facilitates targeted protein degradation, making it a valuable tool for researchers in drug discovery and chemical biology.
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