N-Trifluoroacetyladriamycin

Catalog No.: A73956
Endogenous Metabolite
N-Trifluoroacetyladriamycin (AD-41) is a chemotherapeutic agent that primarily targets tumor cells through its antitumor activity. This compound is notable for its significant accumulation in various tissues, including the small intestine, liver, kidneys, spleen, large intestine, lung, and heart, which correlates with its biological efficacy. As a metabolite of Valrubicin, it plays a crucial role in the inhibition of bladder cancer and is relevant in studies investigating metabolic pathways and antitumor mechanisms associated with its derivatives.
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Size Price Stock Qty
5mg
$430.00
In stock
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Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN-Trifluoroacetyladriamycin (AD-41) is a chemotherapeutic agent that primarily targets tumor cells through its antitumor activity. This compound is notable for its significant accumulation in various tissues, including the small intestine, liver, kidneys, spleen, large intestine, lung, and heart, which correlates with its biological efficacy. As a metabolite of Valrubicin, it plays a crucial role in the inhibition of bladder cancer and is relevant in studies investigating metabolic pathways and antitumor mechanisms associated with its derivatives.
Product Information
Catalog NumA73956
FormulaC29H28F3NO12
Molecular Weight639.53
CAS Number26295-56-7
SMILESOC1=C(C(C2=CC=CC(OC)=C2C3=O)=O)C3=C(O)C4=C1C[C@](C(CO)=O)(O)C[C@@H]4O[C@H]5C[C@@H]([C@@H]([C@@H](O5)C)O)NC(C(F)(F)F)=O
SynonymsAD-41
Useful Calculator

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