N6F11

Catalog No.: A27039
Ferroptosis Inducer
N6F11 is a selective ferroptosis inducer that targets TRIM25 to promote the degradation of GPX4 in cancer cells while preserving immune cell functionality. This compound triggers HMGB1-dependent antitumor immunity, activating CD8+ T cells and enhancing the immune response against tumors. N6F11 is suitable for research applications focused on cancer therapy and the mechanisms underlying ferroptosis.
Grouped product items
Size Price Stock Qty
1mg
$20.00
In stock
5mg
$35.00
In stock
10mg
$50.00
In stock
25mg
$85.00
In stock
50mg
$130.00
In stock
100mg
$205.00
In stock
Bulk Size
Bulk Discount
Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionN6F11 is a selective ferroptosis inducer that targets TRIM25 to promote the degradation of GPX4 in cancer cells while preserving immune cell functionality. This compound triggers HMGB1-dependent antitumor immunity, activating CD8+ T cells and enhancing the immune response against tumors. N6F11 is suitable for research applications focused on cancer therapy and the mechanisms underlying ferroptosis.
Product Information
Catalog NumA27039
FormulaC13H8Cl2N2OS
Molecular Weight311.19
CAS Number851398-76-0
SMILESClC1=CC=C(C2=CC3=C(C(NC(CCl)=N3)=O)S2)C=C1
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