Fig. 1 · Structure
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NADPH
Reducing Agent
NADPH serves as a critical reducing agent involved in redox reactions, acting primarily as a coenzyme for glutathione reductase (GR), thioredoxin reductase (TrxR), and NADPH oxidase (NOX). This metabolite plays a key role in maintaining cellular redox homeostasis and exhibits antioxidant properties by facilitating the regeneration of glutathione (GSH) and thioredoxin (Trx). Additionally, NADPH is instrumental in generating superoxide anions through NOX, thereby influencing oxidative stress and immune responses. Its applications extend to the study of oxidative stress-related diseases, including cardiovascular and neurodegenerative disorders, as well as cancer, and it is integral in exploring immune regulatory mechanisms.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 53-57-6 |
| Applications | Reducing Agent |
| Formula | C21H30N7O17P3 |
| Molecular Weight | 745.42 |
| SMILES | O=P(O)(O)O[C@H]1[C@H](N2C3=NC=NC(N)=C3N=C2)O[C@@H]([C@H]1O)COP(OP(OC[C@H]4O[C@@H](N5C=C(CC=C5)C(N)=O)[C@@H]([C@@H]4O)O)(O)=O)(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.