Fig. 1 · Structure

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Nafimidone hydrochloride

Anticonvulsant

Nafimidone hydrochloride is an anticonvulsant compound that effectively penetrates the blood-brain barrier. It demonstrates significant anticonvulsant activity in models of kindled amygdaloid seizures, although caution is advised due to its narrow therapeutic window and potential epileptogenic effects at elevated doses. Nafimidone hydrochloride serves as a valuable reagent for research in epilepsy and the mechanisms underlying seizure activity.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 70891-37-1
Applications Anticonvulsant
Formula C15H13ClN2O
Molecular Weight 272.73
SMILES
O=C(CN1C=NC=C1)C2=CC3=C(C=CC=C3)C=C2.Cl

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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