Fig. 1 · Structure
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Nafimidone
Antiepileptic compound
Nafimidone is a stable and brain-penetrant antiepileptic compound that primarily targets seizure activity. It demonstrates effective anticonvulsant properties in the kindled amygdaloid seizure model, making it a valuable tool for epilepsy research. Despite its efficacy, nafimidone has a narrow therapeutic window and may induce epileptogenic effects at elevated doses, highlighting the importance of dosage considerations in research applications.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 64212-22-2 |
| Applications | Antiepileptic compound |
| Formula | C15H12N2O |
| Molecular Weight | 236.27 |
| SMILES | O=C(CN1C=NC=C1)C2=CC3=C(C=CC=C3)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.