Fig. 1 · Structure

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Naltriben mesylate

Cat. No. A62324 CAS 122517-78-6

δ2-opioid Receptor Antagonist/TRPM7 Activator

Naltriben mesylate is a potent antagonist of the δ2-opioid receptor and an activator of TRPM7 channels. It demonstrates high affinity, with Ki values of 0.013 nM for the δ receptor, alongside 19 nM and 152 nM for μ and κ receptors, respectively. Research indicates that Naltriben mesylate enhances glioblastoma cell migration and invasion, making it a valuable tool for studies related to neurological diseases and cancer biology.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 122517-78-6
Applications δ2-opioid Receptor Antagonist/TRPM7 Activator
Formula C27H29NO7S
Molecular Weight 511.59
SMILES
CS(=O)(O)=O.O[C@@]1(CC(C(C=CC=C2)=C2O3)=C3[C@]4([H])OC5=C6O)[C@]74C5=C(C=C6)C[C@@]1([H])N(CC8CC8)CC7

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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