Naproxen etemesil

Catalog No.: A13052

COX-1 and COX-2 inhibitor

Naproxen etemesil

Naproxen etemesil Chemical Structure

CAS NO. 385800-16-8

Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay.

Availability: In stock

Package Price Qty
5 mg

Regular Price: $225.00

Special Price $180.00

10 mg

Regular Price: $388.00

Special Price $310.40

50 mg

Regular Price: $1,150.00

Special Price $920.00

100 mg

Regular Price: $2,300.00

Special Price $1,840.00

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Biological Activity

Naproxen etemesil is a lipophilic, non-acidic, inactive prodrug of naproxen that is hydrolysed to pharmacologically active Naproxen once absorbed. Naproxen is a COX-1 and COX-2 inhibitor with IC50s of 8.72 and 5.15 μM, respectively in cell assay.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 29.73 mL 148.63 mL 297.27 mL
0.5 mM 5.95 mL 29.73 mL 59.45 mL
1 mM 2.97 mL 14.86 mL 29.73 mL
5 mM 0.59 mL 2.97 mL 5.95 mL

*The above data is based on the productmolecular weight 336.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A13052
Actions Inhibitor
CAS No. 385800-16-8
Formula C17H20O5S
M. Wt 336.4
Purity >98%
Synonyms LT-NS 001; MX 1094, MX-1094, MX1094
SMILES O=C(OCCS(C)(=O)=O)[[email protected]@H](C)C1=CC2=CC=C(OC)C=C2C=C1
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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