Fig. 1 · Structure
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NAT6-297775
SHP-2 Inhibitor
NAT6-297775 is a selective inhibitor of the non-receptor protein tyrosine phosphatase SHP-2, exhibiting an IC50 value of 2.5 μM. This compound is capable of inhibiting the RAS/MAP kinase signaling pathway, which is crucial in various cellular processes. NAT6-297775 is particularly relevant for cancer research, including studies focused on leukemia and related malignancies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1348433-02-2 |
| Applications | SHP-2 Inhibitor |
| Formula | C25H36N6O2 |
| Molecular Weight | 452.60 |
| SMILES | N(CC1CCCCC1)[C@H]2O[C@@]3([C@H](CO[C@@]3(C2)[H])N4C(=NN=N4)C5=CC(CN6CCCC6)=CC=C5)[H] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.