Fig. 1 · Structure

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Naxaprostene

Prostacyclin Analogue

Naxaprostene is a selective prostacyclin analogue that primarily targets IP receptors, exhibiting partial agonistic activity. This compound effectively inhibits ADP-induced platelet aggregation, demonstrating significant antithrombotic properties. Naxaprostene has been shown to prevent thrombosis in models such as rabbit carotid artery, making it a valuable tool in cardiovascular research and studies focusing on platelet function and vascular health.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 87269-59-8
Applications Prostacyclin Analogue
Formula C25H32O4
Molecular Weight 396.52
Synonyms EL 784
SMILES
O[C@@H](C1CCCCC1)/C=C/[C@@H]2[C@]3([H])[C@@](C[C@H]2O)([H])C/C(C3)=C\C4=CC(C(O)=O)=CC=C4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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