NBD peptide is a selective inhibitor of the NF-κB signaling pathway, acting by disrupting the interaction between NEMO and the IKK complex. This inhibition leads to reduced production of pro-inflammatory cytokines, showcasing its anti-inflammatory properties. Additionally, NBD peptide demonstrates immunosuppressive effects through modulation of immune cell activity. The incorporation of the cell-penetrating HIV-TAT peptide enhances its cellular uptake, facilitating its application in various research contexts.
NBD peptide is a selective inhibitor of the NF-κB signaling pathway, acting by disrupting the interaction between NEMO and the IKK complex. This inhibition leads to reduced production of pro-inflammatory cytokines, showcasing its anti-inflammatory properties. Additionally, NBD peptide demonstrates immunosuppressive effects through modulation of immune cell activity. The incorporation of the cell-penetrating HIV-TAT peptide enhances its cellular uptake, facilitating its application in various research contexts.
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