NBI-27914 is a potent and selective antagonist of corticotropin-releasing factor receptor 1 (CRFR1), a member of the G protein-coupled receptor (GPCR) superfamily. By selectively blocking CRFR1, NBI-27914 is useful for studying stress-related pathways and disorders mediated by CRF signaling, such as anxiety and depression.
NBI-27914 is a potent and selective antagonist of corticotropin-releasing factor receptor 1 (CRFR1), a member of the G protein-coupled receptor (GPCR) superfamily. By selectively blocking CRFR1, NBI-27914 is useful for studying stress-related pathways and disorders mediated by CRF signaling, such as anxiety and depression.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
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