NBTIs-IN-5 is a novel bacterial topoisomerase inhibitor targeting DNA gyrase. It exhibits an IC50 of 1.5 μM against Mycobacterium abscessus, demonstrating potent inhibition of this pathogen's DNA gyrase activity. Additionally, NBTIs-IN-5 shows a minimum inhibitory concentration (MIC90) of 0.4 μM, effectively suppressing bacterial growth. This compound is valuable for research applications focused on antibiotic discovery and understanding bacterial topoisomerase function.
NBTIs-IN-5 is a novel bacterial topoisomerase inhibitor targeting DNA gyrase. It exhibits an IC50 of 1.5 μM against Mycobacterium abscessus, demonstrating potent inhibition of this pathogen's DNA gyrase activity. Additionally, NBTIs-IN-5 shows a minimum inhibitory concentration (MIC90) of 0.4 μM, effectively suppressing bacterial growth. This compound is valuable for research applications focused on antibiotic discovery and understanding bacterial topoisomerase function.
This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:
