NC-001

Catalog No.: A31718
Apoptosis Inducer
NC-001 is a selective apoptosis inducer that primarily targets renal proximal tubular cells and renal cancer cells. This compound has demonstrated the ability to inhibit tumor growth in clear cell renal cell carcinoma (CCRCC) xenograft models, making it a valuable tool for investigating metastatic renal cell carcinoma. Its mechanism of action positions NC-001 as a promising candidate for research focused on renal cancer therapies.
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5mg
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50mg
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Free Delivery on orders over $500
Research use only. We do not sell to patients.

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Adooq Products cited in reputable paper
Science VOLUME 380, ISSUE 6663 (2023)
Science VOLUME 369, ISSUE 6510 (2020)
Science VOLUME 356, ISSUE 6336 (2017)
Cell Vol. 185 Issue 23 p4428-4447.e28
Cell Vol 177, Issue 7, p1933-1947.e25
Cell Vol 156, Issue 5, p857-1114
Nature Volume 622 Issue 7982 (2023)
Nature volume 620, pages890-897 (2023)
Nature volume 610, pages540-546 (2022)
Nature volume 588, pages83-88 (2020)
Nature volume 574, pages268-272 (2019)
Nature volume 573, pages539-545 (2019)
Nature volume 567, pages118-122 (2019)
Nature volume 551, pages639-643 (2017)
Nature volume 551, pages247-250 (2017)
Nature volume 548, pages356-360 (2017)
Nature volume 545, pages187-192 (2017)
Biological Activity
DescriptionNC-001 is a selective apoptosis inducer that primarily targets renal proximal tubular cells and renal cancer cells. This compound has demonstrated the ability to inhibit tumor growth in clear cell renal cell carcinoma (CCRCC) xenograft models, making it a valuable tool for investigating metastatic renal cell carcinoma. Its mechanism of action positions NC-001 as a promising candidate for research focused on renal cancer therapies.
Product Information
Catalog NumA31718
FormulaC25H41N7O6
Molecular Weight535.64
CAS Number1237540-68-9
SMILESO=C([C@H]1N(C([C@H](C)NC(CN=[N+]=[N-])=O)=O)CCC1)N[C@@H](CCCC)C(N[C@@H](CC(C)C)C([C@]2(C)OC2)=O)=O
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