NCGC00092410 is a selective glucocerebrosidase chaperone that enhances the enzyme's activity and lysosomal localization in mutant cell lines. With an IC50 of 31 nM, it demonstrates notable potency without affecting related hydrolases at concentrations up to 77 μM. This reagent is primarily utilized in research focused on Gaucher disease, providing insights into therapeutic strategies for this lysosomal storage disorder.
NCGC00092410 is a selective glucocerebrosidase chaperone that enhances the enzyme's activity and lysosomal localization in mutant cell lines. With an IC50 of 31 nM, it demonstrates notable potency without affecting related hydrolases at concentrations up to 77 μM. This reagent is primarily utilized in research focused on Gaucher disease, providing insights into therapeutic strategies for this lysosomal storage disorder.
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