Biological Activity
NCH 51 is a cell-permeable prodrug that is intracellularly converted to a potent HDAC inhibitor, with an IC50 of 48 nM.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.6 mL | 128.02 mL | 256.04 mL |
0.5 mM | 5.12 mL | 25.6 mL | 51.21 mL |
1 mM | 2.56 mL | 12.8 mL | 25.6 mL |
5 mM | 0.51 mL | 2.56 mL | 5.12 mL |
*The above data is based on the productmolecular weight 390.56. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
Catalog Num | A15355 |
---|---|
Actions | Inhibitor |
CAS No. | 848354-66-5 |
Formula | C20H26N2O2S2 |
M. Wt | 390.56 |
Purity | >98% |
Synonyms | PTACH |
SMILES | CC(C)C(=O)SCCCCCCC(=O)NC1=NC(=CS1)C2=CC=CC=C2 |
Storage | Store lyophilized at -20ºC, keep desiccated. |
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