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NCS-MP-NODA

Bifunctional Chelator

NCS-MP-NODA (NODA-Bz-SCN) is a bifunctional chelator designed to specifically bind to the labeled peptide DK222, targeting PD-L1 with high affinity. This reagent facilitates the synthesis of fluorinated radioactive analogs, such as [18/19F]DK222, using the aluminum fluoride method. [18F]DK222 enables in vivo quantification of PD-L1 expression through PET imaging in various xenograft cancer models, making it a valuable tool for cancer research and immunotherapy studies.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	1374994-81-6
Applications	Bifunctional Chelator
Formula	C₁₈H₂₄N₄O₄S
Molecular Weight	392.47
Synonyms	NODA-Bz-SCN
SMILES	O=C(CN1CCN(CCN(CC1)CC2=CC=C(C=C2)N=C=S)CC(O)=O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.