Fig. 1 · Structure
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ND-378
MMP-2 Inhibitor
ND-378 is a potent and selective inhibitor of matrix metalloproteinase-2 (MMP-2), exhibiting a Ki value of 230 nM. It is primarily utilized in research investigating the mechanisms and therapies associated with spinal cord injury (SCI). By inhibiting MMP-2, ND-378 can help elucidate the role of extracellular matrix remodeling in neurological conditions and potential therapeutic strategies.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1807453-72-0 |
| Applications | MMP-2 Inhibitor |
| Formula | C18H19NO4S2 |
| Molecular Weight | 377.48 |
| SMILES | O=C(C)NCC1=CC=C(C=C1)OC2=CC=C(S(=O)(CC3SC3)=O)C=C2 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.